Scratch test looks for what type of hypersensitivity reaction?

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Multiple Choice

Scratch test looks for what type of hypersensitivity reaction?

Explanation:
Scratch testing identifies immediate, IgE-mediated allergic responses, i.e., Type I hypersensitivity. If a person is sensitized to an allergen, the allergen cross-links IgE on mast cells in the skin, triggering degranulation and release of histamine and other mediators, producing a localized wheal-and-flare within about 15–20 minutes. This distinguishes Type I from other hypersensitivity types, which are either antibody-mediated cytotoxic (Type II), immune complex–mediated (Type III), or delayed-type T-cell–mediated (Type IV).

Scratch testing identifies immediate, IgE-mediated allergic responses, i.e., Type I hypersensitivity. If a person is sensitized to an allergen, the allergen cross-links IgE on mast cells in the skin, triggering degranulation and release of histamine and other mediators, producing a localized wheal-and-flare within about 15–20 minutes. This distinguishes Type I from other hypersensitivity types, which are either antibody-mediated cytotoxic (Type II), immune complex–mediated (Type III), or delayed-type T-cell–mediated (Type IV).

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